As Cleo Lovedrop heads off for college at the local art school, shes haunted by her melancholic past: a lost love, a lost child. Friends and enemies live their lives around her, as trouble and dissent brews amongst them: an unseen social assailant spreads slander about Cleo, she is forced to deal with her two brusque roommates, and discovers unsolved mysteries about the girl who lived in her room previously. Elsewhere, Trilby deals with unsettled emotional and sexual issues, and keeping her secret habits hidden from everyone. And Audrey comes to the realization that, despite all her efforts, she always causes her friends distress, while Fern, a peculiar, deformed girl who lives in an isolated mansion in the bayous, begins to notice Cleo and her friends. As the moon grows full and lunar rays shine down, lunacy and moon-calves run free.